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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA1
All Species:
33.03
Human Site:
Y486
Identified Species:
72.67
UniProt:
Q15418
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15418
NP_001006666.1
735
82723
Y486
Y
D
D
G
K
H
V
Y
L
V
T
E
L
M
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001104305
745
83841
Y494
F
D
D
G
R
Y
V
Y
L
V
T
D
L
M
K
Dog
Lupus familis
XP_544479
744
83915
Y495
Y
D
D
G
K
H
V
Y
L
V
T
E
L
M
R
Cat
Felis silvestris
Mouse
Mus musculus
P18653
724
81576
Y475
Y
D
D
G
K
H
V
Y
L
V
T
E
L
M
R
Rat
Rattus norvegicus
Q63531
735
82865
Y486
Y
D
D
S
K
H
V
Y
L
V
T
E
L
M
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513942
700
79225
E454
K
Y
V
Y
V
V
T
E
L
M
K
G
G
E
L
Chicken
Gallus gallus
P18652
752
84421
Y503
Y
D
D
G
K
Y
V
Y
L
V
T
E
L
M
R
Frog
Xenopus laevis
P10665
733
82620
Y484
Y
K
E
G
N
S
I
Y
V
V
T
E
L
M
R
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
Y488
Y
D
E
G
R
F
V
Y
L
V
T
E
L
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
C691
H
G
T
F
R
E
K
C
E
T
W
I
V
M
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
Y522
Y
E
D
E
T
A
I
Y
M
I
E
E
L
C
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
73
94.3
N.A.
97
97.5
N.A.
79.7
90
84.9
75.1
N.A.
24.3
N.A.
58.2
N.A.
Protein Similarity:
100
N.A.
83.4
95.5
N.A.
97.6
98.9
N.A.
86.5
93.2
90.1
85.2
N.A.
36.4
N.A.
73
N.A.
P-Site Identity:
100
N.A.
66.6
100
N.A.
100
93.3
N.A.
6.6
93.3
60
73.3
N.A.
6.6
N.A.
33.3
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
93.3
N.A.
13.3
100
80
93.3
N.A.
26.6
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% C
% Asp:
0
64
64
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
10
19
10
0
10
0
10
10
0
10
73
0
10
19
% E
% Phe:
10
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
64
0
0
0
0
0
0
0
10
10
0
0
% G
% His:
10
0
0
0
0
37
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
19
0
0
10
0
10
0
0
0
% I
% Lys:
10
10
0
0
46
0
10
0
0
0
10
0
0
0
19
% K
% Leu:
0
0
0
0
0
0
0
0
73
0
0
0
82
0
10
% L
% Met:
0
0
0
0
0
0
0
0
10
10
0
0
0
82
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
28
0
0
0
0
0
0
0
0
0
55
% R
% Ser:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
10
0
10
0
0
10
73
0
0
0
0
% T
% Val:
0
0
10
0
10
10
64
0
10
73
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
73
10
0
10
0
19
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _